“Inflammation is absolutely necessary for survival. Inflammation is our body’s response to invaders or injuries. It’s the sunburn after a long day at the beach. It’s the fever and aches that occur when your body is fighting off a virus.”
PEA- The Miracle Molecule
OCTOBER, 2021
Inflammation is absolutely necessary for survival. Inflammation is our body’s response to invaders or injuries. It’s the sunburn after a long day at the beach. It’s the fever and aches that occur when your body is fighting off a virus. It’s the pain and swelling after twisting an ankle. All of these responses are examples of inflammation that promote healing and that protect the body from further harm. Yet for many people the inflammatory response becomes chronic and instead of protecting and healing the body, inflammation begins to wreak havoc.
This is where our Hero comes in: Palmitoylethanolamide, otherwise known as, PEA. Our body produces PEA to protect and repair tissues and minimize pain.* PEA is found in nearly all animal tissues, human breast milk, and many foods. Since its discovery in 1957, PEA has been studied extensively for its anti-inflammatory, neuro-protective and analgesic properties.* The reason PEA provides such amazing benefits is because it targets inflammation at its source: the mast cells and glial cells.*
IMast cells and glial cells are the first line of defense from threats from the outside world. Mast cells are located throughout the body and are concentrated in areas that come in contact with the outside world, like skin, lungs, and the gut. Glial cells are part of the nervous system. They protect and defend the nervous system, including the brain, from injury and infection.
When mast cells and glial cells are over responsive, inflammation and tissue damage can begin to occur. PEA acts as a sort of regulator and helps to keep these cells in check.*
Because PEA plays a key role in reducing inflammation and maintaining homeostasis the effects of supplementing with PEA are wide reaching:
1
Reduced Pain
2
Healthy Immune Response
3
Promotes Restful Sleep
4
Improved Mood
5
Supports Muscle Recovery
So if you need a boost to your overall health and wellbeing, PEA may be the miracle you’re looking for.*
SAFE AND SIDE EFFECT FREE
At this time there are over 900 published studies on PEA. PEA is safe and no side effects have been reported with its use, even at the highest doses.
Learn More >>References
1. Mattace Raso, Giuseppina et al. “Palmitoylethanolamide in CNS health and…” Pharmacological research vol. 86 (2014): 32-41. doi:10.1016/j.phrs.2014.05.006 https://pubmed.ncbi.nlm.nih.gov/24844438/
2. Hesselink, J. M.. “Evolution in pharmacologic thinking around the natural analgesic palmitoylethanolamide: from nonspecific resistance to PPAR-α agonist and effective nutraceutical.” Journal of Pain Research 6 (2013): 625 - 634. https://api.semanticscholar.org/CorpusID:8705763
3. Gabrielsson L, Mattsson S, Fowler C. “Palmitoylethanolamide for the Treatment of Pain: Pharmacokinetics, Safety and Efficacy.” British Journal of Clinical Pharmacology 82.4(2016): 932–942.PMC. Web.18 Mar. 2018. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094513/
4. Cruccu, Giorgio et al. “Micronized Palmitoylethanolamide: A Post Hoc Analysis of a Controlled Study in Patients with Low Back Pain…” CNS & neurological disorders drug targets vol. 18,6 (2019): 491-495. doi:10.2174/1871527318666190703110036 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132032/
5. Keppel Hesselink, Jan M, and David J Kopsky. “Palmitoylethanolamide, a neutraceutical, in nerve compression syndromes: efficacy and safety in….” Journal of pain research vol. 8 729-34. 23 Oct. 2015, doi:10.2147/JPR.S93106 https://pubmed.ncbi.nlm.nih.gov/26604814/
6. D’Amico, Ramona et al. “ALIAmides Update: Palmitoylethanolamide and Its Formulations on Management of…” International journal of molecular sciences vol. 21,15 5330. 27 Jul. 2020, doi:10.3390/ijms21155330 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432736/
7. Cordaro, Marika et al. “An Update of Palmitoylethanolamide and Luteolin Effects in Preclinical and Clinical Studies of Neuroinflammatory Events.” Antioxidants (Basel, Switzerland) vol. 9,3 216. 5 Mar. 2020, doi:10.3390/antiox9030216 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139331