Palmitoylethanolamide (PEA) is natural and found in nearly all animal tissues, human breast milk, and many foods. Since its discovery in 1957, PEA has been studied extensively for its anti-inflammatory, neuro-protective and analgesic properties.

1. SUPPORTS HEALTHY JOINTS

A double-blind placebo-controlled study ran in adults with mild to moderate knee pain and stiffness had 111 participants randomized to receive 300 mg PEA, 600 mg PEA or a placebo each day for 8 weeks. There was a significant reduction in pain, stiffness, and anxious feelings in the PEA groups compared to placebo.

2. SUPPORTS BALANCED MOOD

A randomized double-blind placebo-controlled study of 58 patients with depressive symptoms was administered.They received either PEA or placebo in addition to citalopram for six weeks.The PEA group demonstrated significantly greater improvement in depressive symptoms compared to the placebo group throughout the trial period.

3. SUPPORTS SLEEP QUALITY

In a study of 42 patients awaiting surgery for nerve compression in the wrist who suffered from sleep disruption and painful symptoms were randomized into two groups. One group received PEA (600 mg twice daily) during the pre- and post surgery periods, while the other group did not receive any treatment except surgical therapy. At the end of the pre-surgery period, there was a highly significant improvement among the PEA group in overall sleep quality as well as a significant reduction of pain.

4. SUPPORTS MUSCLE RECOVERY

In a study of 28 healthy young male participants, results indicated PEA supplementation aids in muscle recovery.

5. SIDE EFFECT FREE

PEA occurs naturally in the body and in many foods. No side effects have been reported with its use, even at the highest doses.